[{"data":1,"prerenderedAt":109},["ShallowReactive",2],{"content-route-/en/about/evidence-methodology":3},{"state":4,"owner":4,"route":5,"locale":6,"template":7,"content":11,"projection":96,"alternates":100},"target","/en/about/evidence-methodology","en-US",{"kind":8,"family":9,"sectionKeys":10},"trust","site-page",[],{"kind":8,"title":12,"description":13,"firstPublished":14,"evidenceAsOf":15,"lastUpdated":14,"changeNote":16,"body":17},"Evidence methodology","How Candipedia Research selects sources, assesses bodies of evidence, states uncertainty, and triggers reassessment.","2026-07-14",null,"Published the source hierarchy, evidence levels, and reassessment rules.",{"type":18,"value":19,"toc":89},"minimark",[20,24,29,32,35,39,68,71,75],[21,22,23],"p",{},"Candipedia Research evaluates an exact claim, outcome, and population. A single paper can contribute to a conclusion but does not receive or determine a body-of-evidence level by itself.",[25,26,28],"h2",{"id":27},"source-hierarchy","Source hierarchy",[21,30,31],{},"We prefer current clinical guidelines and public-health or regulator sources for care and safety rules; systematic reviews and meta-analyses for synthesis; and controlled trials and well-designed observational studies for specific effects. Laboratory, animal, small pilot, expert-opinion, and anecdotal material can provide context but cannot be presented as established human benefit.",[21,33,34],{},"Sources are checked for identity, study design, population, applicability, date, funding or conflicts when reported, and correction, retraction, withdrawal, or supersession status. Important conclusions link to their underlying sources.",[25,36,38],{"id":37},"evidence-levels","Evidence levels",[40,41,42,50,56,62],"ul",{},[43,44,45,49],"li",{},[46,47,48],"strong",{},"Strong:"," consistent, directly applicable evidence with low enough uncertainty to support a stable conclusion.",[43,51,52,55],{},[46,53,54],{},"Moderate:"," useful human evidence supports the conclusion, but important limitations or uncertainty remain.",[43,57,58,61],{},[46,59,60],{},"Early:"," preliminary, indirect, small, or not yet replicated evidence that is not ready to carry a firm practical conclusion.",[43,63,64,67],{},[46,65,66],{},"Unclear:"," evidence is insufficient, conflicting, or too poorly applicable for a dependable conclusion.",[21,69,70],{},"The benefit or effect verdict, strength of evidence, and safety status are separate judgments. Uncertainty and meaningful disagreement are shown beside the conclusion they affect.",[25,72,74],{"id":73},"updates-and-reassessment","Updates and reassessment",[21,76,77,78,83,84,88],{},"Health conclusions are reviewed by their stated review date and sooner when a relevant guideline, regulator notice, product-access change, major study, correction, retraction, source expiry, broken source link, or safety signal appears. A reassessment may record that the practical answer did not change. Material changes and corrections are dated in the ",[79,80,82],"a",{"href":81},"/en/about/changes/","public changes"," or ",[79,85,87],{"href":86},"/en/about/corrections/log/","corrections log",".",{"title":90,"searchDepth":91,"depth":91,"links":92},"",2,[93,94,95],{"id":27,"depth":91,"text":28},{"id":37,"depth":91,"text":38},{"id":73,"depth":91,"text":74},{"sources":97,"claims":98,"safety":99},[],[],[],[101,104,107],{"rel":102,"hreflang":6,"href":103},"alternate","https://candipedia.org/en/about/evidence-methodology/",{"rel":102,"hreflang":105,"href":106},"pl-PL","https://candipedia.org/pl/o-nas/metodologia-dowodow/",{"rel":102,"hreflang":108,"href":103},"x-default",1784685064825]