Candipedia — Meaningful changes https://candipedia.org/en/research/changes/ Evidence changes that change or confirm practical action, in English. en-US Comparing seven consumer gut microbiome testing services https://candipedia.org/en/research/consumer-microbiome-test-comparison-2026/ https://candipedia.org/en/research/consumer-microbiome-test-comparison-2026/ https://pubmed.ncbi.nlm.nih.gov/41748906/ https://candipedia.org/en/research/evidence/broad-candida-claims/ No practical change. The comparison supports caution when interpreting consumer stool microbiome reports but cannot validate or invalidate a specific Candida diagnosis or determine patient benefit. Wed, 15 Jul 2026 00:00:00 GMT Candipedia Research Nystatin for presumed Candida-related systemic symptoms https://candipedia.org/en/research/nystatin-candida-systemic-symptoms-1990/ https://candipedia.org/en/research/nystatin-candida-systemic-symptoms-1990/ https://pubmed.ncbi.nlm.nih.gov/2247104/ https://candipedia.org/en/research/evidence/broad-candida-claims/ No practical change. The trial does not support long-term nystatin for the tested broad systemic-symptom syndrome, while its result must not be generalized to other drugs or recognized candidiasis. Wed, 15 Jul 2026 00:00:00 GMT Candipedia Research Probiotics alongside antifungals for vulvovaginal candidiasis https://candipedia.org/en/research/probiotics-for-vvc-cochrane-2017/ https://candipedia.org/en/research/probiotics-for-vvc-cochrane-2017/ https://www.cochrane.org/evidence/CD010496_probiotics-vulvovaginal-candidiasis-non-pregnant-women https://candipedia.org/en/research/evidence/broad-candida-claims/ No practical change. The review does not establish durable benefit, recurrence prevention, monotherapy benefit, or a recommendation for a probiotic product or strain. Wed, 15 Jul 2026 00:00:00 GMT Candipedia Research How patients and clinicians experience recurrent-thrush diagnosis https://candipedia.org/en/research/rvvc-diagnostic-experiences-2026/ https://candipedia.org/en/research/rvvc-diagnostic-experiences-2026/ https://pubmed.ncbi.nlm.nih.gov/41628983/ https://candipedia.org/en/research/evidence/recurrent-vaginal-yeast-symptoms/ No practical change. The study informs history and appointment preparation but cannot establish diagnosis or prove that a tool improves outcomes. Wed, 15 Jul 2026 00:00:00 GMT Candipedia Research Maintenance treatment for recurrent vulvovaginal candidiasis https://candipedia.org/en/research/rvvc-maintenance-treatment-review-2022/ https://candipedia.org/en/research/rvvc-maintenance-treatment-review-2022/ https://pmc.ncbi.nlm.nih.gov/articles/PMC8744138/ https://candipedia.org/en/research/evidence/recurrent-vaginal-yeast-symptoms/ No practical change. The review supports maintenance as control during treatment, not a reliable long-term cure or an individualized regimen ranking. Wed, 15 Jul 2026 00:00:00 GMT Candipedia Research Oral versus topical maintenance treatment for RVVC https://candipedia.org/en/research/rvvc-oral-vs-topical-maintenance-2026/ https://candipedia.org/en/research/rvvc-oral-vs-topical-maintenance-2026/ https://link.springer.com/article/10.1186/s12905-026-04356-8 https://candipedia.org/en/research/evidence/recurrent-vaginal-yeast-symptoms/ No practical change. The direct evidence preserves the current no-route-ranking conclusion rather than establishing equivalence or superiority. Wed, 15 Jul 2026 00:00:00 GMT Candipedia Research How recurrent vulvovaginal candidiasis affects quality of life https://candipedia.org/en/research/rvvc-quality-of-life-2019/ https://candipedia.org/en/research/rvvc-quality-of-life-2019/ https://pubmed.ncbi.nlm.nih.gov/31270690/ https://candipedia.org/en/research/evidence/recurrent-vaginal-yeast-symptoms/ No practical change. The study supports taking the burden seriously but does not determine diagnosis, treatment, or safety routing. Wed, 15 Jul 2026 00:00:00 GMT Candipedia Research Small-intestinal fungal overgrowth in a specialist referral cohort https://candipedia.org/en/research/sifo-aspirate-symptoms-2013/ https://candipedia.org/en/research/sifo-aspirate-symptoms-2013/ https://pubmed.ncbi.nlm.nih.gov/23574267/ https://candipedia.org/en/research/evidence/broad-candida-claims/ No practical change. This study supports an aspirate-defined clinical SIFO boundary and shows that symptoms alone were poor predictors; it does not validate broad symptom-based Candida diagnoses or establish treatment benefit. Wed, 15 Jul 2026 00:00:00 GMT Candipedia Research Oral and topical treatments for uncomplicated vaginal yeast infection https://candipedia.org/en/research/uncomplicated-vvc-treatment-network-analysis-2025/ https://candipedia.org/en/research/uncomplicated-vvc-treatment-network-analysis-2025/ https://pubmed.ncbi.nlm.nih.gov/40157526/ https://candipedia.org/en/research/evidence/recurrent-vaginal-yeast-symptoms/ No practical change. The review updates comparative estimates but supports keeping route choice separate from a strict efficacy ranking. Wed, 15 Jul 2026 00:00:00 GMT Candipedia Research